| Pathway Id | ko00440 |
| Class & Sub-Class | Class: Metabolism Sub-Class: Metabolism of other amino acids |
| Description | Natural products containing carbon-phosphorous bonds; so-called C-P compounds; are derivatives of phosphonate and phosphinate with substitution of alkyl group for hydrogen of phosphorus-hydrogen bonds. C-P compounds have been found in many organisms; but only protists and bacteria; mostly Actinobacteria; have biosynthetic capacity. A common reaction in the biosynthetic pathway is C-P bond forming reaction from phosphoenolpyruvate (PEP) to phosphonopyruvate (PnPy) catalyzed by PEP phosphomutase. 2-Aminoethylphosphonate (AEP) is the most abundant C-P compound in the natural world. AEP derivatives include phosphonoprotein; phosphonoglycan; and phosphonolipid. Other known C-P compounds are bioactive substances used in medicine (antibiotics) and agriculture (herbicide) such as fosfomycin; FR-33289; rhizocticin; and bialaphos. Source: KEGG Database |
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