Pathway Id | ko04136 |
Class & Sub-Class | Class: Cellular Processes Sub-Class: Transport and catabolism |
Description | Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells; and is characterized by the formation of a double-membrane structure called the autophagosome; either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction; vesicle nucleation; elongation and closure; and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists; where autophagy related genes (ATGs) play similar roles in the life cycle. However; autophagy has been relatively less studied in lower eukaryotes. Source: KEGG Database |
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