Pathway Id | ko03040 |
Class & Sub-Class | Class: Genetic Information Processing Sub-Class: Transcription |
Description | After transcription; eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing; introns are excised and exons are joined by a macromolecular complex; the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs); U1; U2; U4; U5; and U6 snRNPs; and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex; but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-; B- and C-complexes) have been identified. Source: KEGG Database |
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